PRODUCT

Exosome

  • Cells secrete exosomes to exchange information with each other.
  • The exosomes in intracellular MVB (Multi-vesicular body) are secreted by fusion of MVB and cell membranes and transferred to the recipient cell.
  • Exosomes have a phospholipid bilayer structure with a size of about 30-150 nm.
  • Exosomes contain various nucleic acids, lipids and proteins such as growth factors and cytokines, etc.

Recent Trends of Exosome Research

Exosome research trends in the last 20 years

  • 6000
  • 4000
  • 2000
  • 0

Year

Source: PubMed, (2001-2021)

  • Recent studies on exosomes are very active because exosomes show various biological activities reflecting the characteristics of the cells secreting them.
  • Recently, academic papers related to exosomes have increased by an average of 30.4% over the past 10 years.

Key Research on Exosomes

화살표

  • 1983

    Confirmation of exosome existence.

  • 1996

    Functional study of exosome, role of Immunoregulatory, etc.

  • 1998 ~ 2001

    Study of DC and cancer cell-derived from exosome, etc.

  • 2006 ~ 2007

    Confirmed cell signal transduction and presence of RNA and miRNA

  • 2013

    Analysis of exosome properties, etc. (CD9, CD63, CD81)

  • 2010 ~ 2020

    Increased studies in diagnosis and drug delivery system research

As exosomes are well adsorbed to the cell,
they are being studied and developed as a drug carrier.

biomarker

Exosomes have the characteristics of secreted mother cells,
so it is being researched and developed as diagnostic markers for various disease.

drug delivery

The Necessity and Limitations of Various Exosomes.

The characteristics of exosomes vary depending on tissues and cells, which makes a necessity of suitable exosome for research purposes

  • Difficulty of securing exosome

  • Burden of time and expenses

  • Special equipment for
    exosome analysis is required

Various types of research exosome STExo™

STExoUltraRepro® with the original technology of STEMON.

  • Inducing large amounts of exosomes for research in various species, tissues, and cells by using digital equipment UltraRepro with the original technology of STEMON.

STExoHigh Quality Exosomes

  • Nanoparticle Tracking Analysis (NTA)
    - Size, distribution, content of exosomes
  • pH measurement
  • Determination of protein content
  • ELISA assay
  • Confocal Microscopy Image Analysis
  • Fluorescent labeling of exosomes

STExoSupply of ready-to-use exosome

  • Supply of various exosomes
  • Reduced research time and expenses for researcher
  • Customized order production available, if necessary